A Straightforward Synthesis of Pyrazolines and Pyrazoles: Palladium??Catalyzed Carbonylative Vinylation–Cyclocondensation Reactions of Aryl Halides

XF Wu, H Neumann, M Beller

Index: Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias European Journal of Organic Chemistry, 2011 , # 25 p. 4919 - 4924

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Citation Number: 8

Abstract

Abstract A novel consecutive one-pot synthesis of pyrazolines and pyrazoles starting from simple aryl halides, styrenes, carbon monoxide, and hydrazines has been established. Palladium-catalyzed carbonylative vinylation of aryl halides gave the corresponding chalcones, which are trapped in situ by addition of hydrazines.