Chemical Communications

Improved synthesis of dithieno [3, 2-b: 2′, 3′-d] thiophene (DTT) and derivatives for cross coupling

J Frey, AD Bond, AB Holmes

Index: Frey, Joseph; Bond, Andrew D.; Holmes, Andrew B. Chemical Communications, 2002 , # 20 p. 2424 - 2425

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Citation Number: 63

Abstract

In the method employed previously for the preparation of 1, based on the early work of De Jong and Janssen, 10 the central ring is assembled starting from the outer two thiophenes. The sulfur bridge is introduced first to give 3,3′-dithienyl sulfide, followed by a CuCl 2 mediated oxidative ring closure. This method afforded unsatisfactory yields, both in our and in others' hands. 11,12 Recently, Hellberg and coworkers introduced a modification to this route in which ...