Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure-activity relationship studies …

S Hirashima, T Suzuki, T Ishida, S Noji…

Index: Journal of Medicinal Chemistry, , vol. 49, # 15 p. 4721 - 4736

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Citation Number: 146

Abstract

... Journal of Medicinal Chemistry. ... limited patient compliance. Therefore, development of an improved therapeutic agent for hepatitis C, especially for genotype 1 hepatitis C, is an urgent medical need. To inhibit HCV ...