Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke

SD Linton, T Aja, PR Allegrini, TL Deckwerth…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 10 p. 2685 - 2691

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Citation Number: 23

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 1, 3, and 9. Compound 3 was also significantly more potent than the parent ether analogue (1) in the monocyte [8] and [9] assay (Table 1). Due to this improved cellular activity, along with the observed relative chemical instability of ...