Synthesis and evaluation of tripeptidyl α-Ketoamides as human rhinovirus 3C protease inhibitors

SH Chen, J Lamar, F Victor, N Snyder…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3531 - 3536

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Citation Number: 26

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... In view of the urgent medical needs for anti-HRV drugs, several reports of substrate based reversible and irreversible enzyme inhibitors have recently appeared in the literature. ...