Tetrahedron

Metallation of pyridin-2-yldiazines. Use of pyridine ring as ortho-directing group. Diazines. Part 45

C Berghian, M Darabantu, A Turck, N Plé

Index: Berghian, Camelia; Darabantu, Mircea; Turck, Alain; Ple, Nelly Tetrahedron, 2005 , vol. 61, # 40 p. 9637 - 9644

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Citation Number: 16

Abstract

Starting from commercial chlorodiazines, we report the synthesis of pyridin-2-yldiazines. The first lithiation and functionalization of these compounds are reported and the regioselectivity of the metallation is discussed. The functionalization via the metallation reaction, provides a new access to substituted pyridin-2-yldiazines, which could be used as building blocks in supramolecules.