Synthesis of Oxazolidines, Thiazolidines, and 5, 6, 7, 8-Tetrahydro-1H, 3H-pyrrolo [1, 2-c] oxazole (or thiazole)-1, 3-diones from β-Hydroxy-or β-Mercapto-α-amino …

…, MM Aly, AM Fahmy, MEY Mansour

Index: Badr, Mahmoud Zarif Amin; Aly, Morsy Mohamed; Fahmy, Atiat Mohamed; Mansour, Mansour Esmael Younis Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 6 p. 1844 - 1847

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Citation Number: 18

Abstract

2-Aryl-4-(ethoxycarbonyl) oxazolidines and thiazolidines (1) were prepared from the corresponding α-amino acid ethyl esters containing either hydroxyl or mercapto groups in the β-position by fusion with some aromatic aldehydes. Dehydrogenation of 1 with N- bromosuccinimide gave the corresponding oxazoles and thiazoles. The oxazolidines and thiazolidines gave Mannich bases on interaction with p-nitrobenzaldehyde and piperidine. ...