The Journal of Organic Chemistry

Enzyme-catalyzed regioselective hydrolysis of aspartate diesters

KA Stein, PL Toogood

Index: Stein, Karin A.; Toogood, Peter L. Journal of Organic Chemistry, 1995 , vol. 60, # 24 p. 8110 - 8112

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Citation Number: 28

Abstract

The application of enzymes to organic synthesis promises to provide improved conversion efficiency, significant increases in reaction rates, and higher selectivity than may be achieved in the corresponding uncatalyzed processes. l While each of these advantages are important, most attention has focused on achieving improved selec-tivity, for example, in the resolution of racemic mixtures or the hydrolysis of meso diester^.^-^ Enzymes have ...