Nucleosides. CIX. 2′??Deoxy?螃??isocytidine, 2??deoxy?螃??uridine, and 2′??deoxy??l??methyl?螃??uridine. Isosteres of deoxycytidine, deoxyuridine and thymidine

CK Chu, U Reichman, KA Watanabe…

Index: Chu,C.K. et al. Journal of Heterocyclic Chemistry, 1977 , vol. 14, p. 1119 - 1121

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Citation Number: 32

Abstract

Abstract 2′-Deoxy-ψ-isocytidine (VIIβ), a 2′-deoxy analog of antileukemic ψ-isocytidine and also a C-nucleoside analog of deoxycytidine, was synthesized from ψ-uridine by making use of the newly discovered pyrimidine to pyrimidine transformation reaction [J. Chem. Soc., 14, 537 (1977)]. 2′-Deoxy-ψ-uridine (IIβ) and 2′-deoxy-l-methyl-ψ-uridine (V), both C-nucleoside analogs of deoxyuridine and thymidine, were also synthesized.