Bismuth chloride mediated synthesis, antimicrobial, and anti-inflammatory activities of new 4-aryl-2-amino thiazoles

T Giridhar, RB Reddy, AS Kumar…

Index: Giridhar; Reddy, R. Buchi; Kumar, A. Sunil; Chandra Mouli Phosphorus, Sulfur and Silicon and the Related Elements, 2008 , vol. 183, # 8 p. 2058 - 2072

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Abstract

Synthesis of 4-aryl-2-Amino thiazoles (3a–u),(4a–c), and (5a–c) was achieved from the reaction of 4-butyl phenacyl chlorides (2a–c) with N-substituted thioureas, in the presence of Bismuth Chloride. The antimicrobial and anti-inflammatory activities of the final products were also studied.