e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Oxygenative cleavage of catechols including protocatechuic acid with molecular oxygen in water catalysed by water-soluble non-heme iron (III) complexes in …
Catechol dioxygenases play key roles in the metabolism of various aromatic compounds, converting aromatics to aliphatics with insertion of molecular oxygen between a C–C bond of a benzene ring. Since the first example of cleavage of 3,5-di-tert-butylcatechol by a simple nonheme iron complex, 1–3 various types of functional models have been developed. 4–7 These model reactions have been performed exclusively in organic solvents such as acetonitrile. Because of ...
