Structure–activity relationships of 1, 3, 5-triazine-2, 4, 6-triones as human gonadotropin-releasing hormone receptor antagonists

Z Guo, D Wu, YF Zhu, FC Tucci, CF Regan…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 16 p. 3685 - 3690

Full Text: HTML

Citation Number: 14

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... of Medicinal Chemistry, Neurocrine Biosciences, Inc., 12790 El Camino Real, San Diego, CA 92130, USA; ... Over 80 triazine-triones were prepared using the chemistry described and a wide variety of substitutions were explored. ...