Tetrahedron

Iodine catalyzed one-pot synthesis of flavanone and tetrahydropyrimidine derivatives via Mannich type reaction

V Kavala, C Lin, CW Kuo, H Fang, CF Yao

Index: Kavala, Veerababurao; Lin, Chunchi; Kuo, Chun-Wei; Fang, Hulin; Yao, Ching-Fa Tetrahedron, 2012 , vol. 68, # 4 p. 1321 - 1329

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Citation Number: 24

Abstract

A variety of functionalized flavanone derivatives and tetrahydropyrimidine derivatives were achieved under remarkably mild conditions. The combination of good to excellent yields, a simple work-up, and the high compatibility of functional groups makes this an attractive synthetic approach to access flavanone and tetrahydropyrimidine derivatives.