1, 2, 4??Oxadiazoles. X. Aryl??1, 2, 4??oxadiazolecarbaldehydes

G Palazzo, L Baiocchi, G Picconi

Index: Palazzo,G. et al. Journal of Heterocyclic Chemistry, 1979 , vol. 16, p. 1469 - 1475

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Citation Number: 4

Abstract

Abstract The synthesis of 5-aryl-1, 2, 4-oxadiazole-3-carbaldehydes and 3-aryl-1, 2, 4- oxadiazole-5-carbaldehydes was attempted through several routes and achieved starting from both the corresponding chloromcthyl and the dichloromethyl derivatives. These aldehydes are stabilized in the hydrated form and this peculiar behavior is discussed on the basis of the relevant spectroscopic data.