Tetrahedron Letters

NiCl 2· 6H 2 O as recyclable heterogeneous catalyst for N-arylation of amines and NH-heterocycles under microwave exposure

AK Gupta, GT Rao, KN Singh

Index: Gupta, Amit Kumar; Tirumaleswara Rao; Singh, Krishna Nand Tetrahedron Letters, 2012 , vol. 53, # 17 p. 2218 - 2221

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Citation Number: 11

Abstract

NiCl2· 6H2O has been proven to be an effective catalyst for the coupling of amines with aryl iodides without ligand under solvent-free conditions employing microwave irradiation. Reactions cleanly result in coupled products in a short reaction time. The catalyst, being heterogeneous, is recovered by filtration and is recyclable.

~46%

~28%

~86%

Synthesis of a 1, 3, 5-benzotriazepine-2, 4-dione based libr...

[Chuckowree, Irina; Ali Syed, Murtaza; Getti, Giulia; Parbhu Patel, Asha; Garner, Hannah; Tizzard, Graham J.; Coles, Simon J.; Spencer, John Tetrahedron Letters, 2012 , vol. 53, # 28 p. 3607 - 3611]