Preparation and evaluation of novel pyrazolo [1, 5-a] pyrimidine acetamides, closely related to DPA-714, as potent ligands for imaging the TSPO 18kDa with PET

V Médran-Navarrete, A Damont…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 6 p. 1550 - 1556

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Citation Number: 6

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 65. In this article, we report the chemical synthesis (Scheme 1 and Scheme 2) of a new subclass of DPA-714 analogues featuring an alkyne triple bond and a short alkane spacer linking the pyrazolopyrimidine scaffold and the fluorine ...