2-Aryl-2-hydroxyethylamine substituted 4-oxo-4, 7-dihydrothieno [2, 3-b] pyridines as broad-spectrum inhibitors of human herpesvirus polymerases

ME Schnute, DJ Anderson, RJ Brideau, FL Ciske…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 12 p. 3349 - 3353

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Citation Number: 25

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... Unfortunately, the availability of a well-tolerated, orally bioavailable, broad-spectrum agent to address herpesvirus infections in the growing immunocompromised population remains an unmet medical need. ...