Journal of the American Chemical Society

Coordination modes of histidine. 2. stereochemistry of the reaction between histidine derivatives and pyridoxal analogs conformational properties of zinc (II) …

L Casella, M Gullotti

Index: Casella, Luigi; Gullotti, Michele Journal of the American Chemical Society, 1981 , vol. 103, # 21 p. 6338 - 6347

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Citation Number: 135

Abstract

Abstract: Pyridoxal reacts with L-histidine, L-histidine methyl ester, histamine and NT- methylhistamine to form 4, 5, 6, 7-tetrahydropyrido [3, 4-d] imidazole compounds through the formation of Schiff base intermediates. The 4, 6-trans isomers of the products are formed with a high degree of stereoselectivity in the case of L-histidine and L-histidine methyl ester. The stereochemistry of these products has been assigned on the basis of their 'Hnmr and ...