N-Hydroxybenzimidazole inhibitors of ExsA MAR transcription factor in Pseudomonas aeruginosa: In vitro anti-virulence activity and metabolic stability

MC Grier, LK Garrity-Ryan, VJ Bartlett…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 11 p. 3380 - 3383

Full Text: HTML

Citation Number: 22

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 5 However, given the same mechanism of action and the similar chemical structures, these newer antibiotics would also be subject to already existing resistance mechanisms. ...