Design, synthesis, and biological evaluation of 14-substituted aromathecins as topoisomerase I inhibitors

MA Cinelli, A Morrell, TS Dexheimer…

Index: Mason, Jeffrey J.; Bergman, Jan Organic and Biomolecular Chemistry, 2007 , vol. 5, # 15 p. 2486 - 2490

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Citation Number: 52

Abstract

... Journal of Medicinal Chemistry. ... J. Med. Chem. , 2008, 51 (15), pp 4609–4619. DOI: 10.1021/jm800259e. Publication Date (Web): July 17, 2008. Copyright © 2008 American Chemical Society. ... Chemistry. Several routes to aromathecin derivatives have been developed. ...