Self??Assembly Approach toward Chiral Bimetallic Catalysts: Bis??Urea??Functionalized (Salen) Cobalt Complexes for the Hydrolytic Kinetic Resolution of Epoxides

J Park, K Lang, KA Abboud…

Index: Park, Jongwoo; Lang, Kai; Abboud, Khalil A.; Hong, Sukwon Chemistry - A European Journal, 2011 , vol. 17, # 7 p. 2236 - 2245

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Citation Number: 29

Abstract

Abstract A series of novel bis-urea-functionalized (salen) Co complexes has been developed. The complexes were designed to form self-assembled structures in solution through intermolecular urea–urea hydrogen-bonding interactions. These bis-urea (salen) Co catalysts resulted in rate acceleration (up to 13 times) in the hydrolytic kinetic resolution (HKR) of rac-epichlorohydrin in THF by facilitating cooperative activation, compared to the ...