The synthesis and SAR study of phenylalanine-derived (Z)-5-arylmethylidene rhodanines as anti-methicillin-resistant Staphylococcus aureus (MRSA) compounds

BA Patel, CR Ashby, D Hardej, TT Talele

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 20 p. 5523 - 5527

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Citation Number: 14

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 27 and 28 the Knoevenagel condensation reaction with aromatic aldehydes provided only the Z-isomer, as determined by the chemical shift of the methine proton ranging from 7.7–8.5 ppm as a singlet (chemical shift for ...