Porphyrin and galactosyl conjugated micelles for targeting photodynamic therapy

…, B Lu, C Chang, SX Cheng, XZ Zhang, RX Zhuo

Index: Wu, De-Qun; Li, Ze-Yong; Li, Cao; Fan, Jian-Jun; Lu, Bo; Chang, Cong; Cheng, Si-Xue; Zhang, Xian-Zheng; Zhuo, Ren-Xi Pharmaceutical Research, 2010 , vol. 27, # 1 p. 187 - 199

Full Text: HTML

Citation Number: 37

Abstract

Abstract Purpose To study the targeting and photodynamic therapy efficiency of porphyrin and galactosyl conjugated micelles based on amphiphilic copolymer galactosyl and mono- aminoporphyrin (APP) incoporated poly (2-aminoethyl methacrylate)-polycaprolactone (Gal- APP-PAEMA-PCL). Methods Poly (2-aminoethyl methacrylate)-polycaprolactone (PAEMA- PCL) was synthesized by the combination of ring opening polymerization and reversible ...