Synthesis

FeF3/I2-catalyzed synthesis of 4-chalcogen-substituted arylamines by direct thiolation of an arene CH bond

XL Fang, RY Tang, XG Zhang, JH Li

Index: Fang, Xiao-Li; Tang, Ri-Yuan; Zhang, Xing-Guo; Li, Jin-Heng Synthesis, 2011 , # 7 p. 1099 - 1105

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Citation Number: 23

Abstract

Abstract An efficient regioselective synthesis of 4-chalcogen-substituted arylamines by FeF 3- catalyzed sulfenylation and selenation of arylamines has been developed. In the presence of FeF 3 and I 2, a variety of arylamines underwent the reaction with disulfides or diselenides to afford the corresponding 4-sulfenyl-or 4-selenenylarylamines in moderate to good yields.