Canadian Journal of Chemistry

Some Observations on the Hydrolysis of the Amides of Primary α-Acetylenic Amines

JN Gardner

Index: Gardner,J.N. Canadian Journal of Chemistry, 1973 , vol. 51, p. 1416 - 1418

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Citation Number: 7

Abstract

Some amides of primary α-acetylenic amines were made from the corresponding α- acetylenic alcohols by the Ritter reaction. Depending upon the other substituents on the carbon atom bearing nitrogen and the ethynyl group, hydrolysis resulted in formation of the α- acetylenic amine or in hydration of the triple bond to yield a ketone.