Xanthan Sulfuric Acid: An Efficient Bio-Supported and Recyclable Solid Acid Catalyst for the Synthesis of 2-minothiazole-5-carboxylates and 2-aminoselenazole-5- …

BS Kuarm, JV Madhav…

Index: Kuarm, Bowroju S.; Madhav, Janganati V.; Rajitha, Bhargavi Letters in Organic Chemistry, 2011 , vol. 8, # 8 p. 549 - 553

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Abstract

An efficient method has been developed for the synthesis of 2-amino thiazole and selenazole-5-carboxylates from β-ketoesters, thiourea or seleno urea and N-bromo succinamide by using Xanthan sulfuric acid as a solid acid catalyst. The reaction work-up is very simple and the catalyst can be easily separated from the reaction mixture and reused several times in subsequent reactions.