Potential anticancer agents. 5-(N-Substituted-aminocarbonyl)-and 5-(N-substituted-aminothiocarbonyl)-5, 6, 7, 8-tetrahydrofolic acids

C Temple Jr, RD Elliott…

Index: Journal of Medicinal Chemistry, , vol. 31, # 3 p. 697 - 700

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Citation Number: 3

Abstract

... ppm, which is consistent with the chemical shifts observed for 4-15 (Table I). In contrast, THF derivatives substituted with an unsaturated group (eg, CO) at N-10 gave ranges of 7.4-7.7 and 7.8-7.9 ppm in which the chemical shift of ... 700 Journal of Medicinal Chemistry, 1988, Vol ...