Abstract A flexible and efficient synthesis of enantiomerically pure 4, 5-substituted 2- oxazolidinones− important target molecules as precursors of pharmacologically active 2- oxazolidinones, β-amino alcohols, β-blockers and azasugar derivatives− is described. As starting materials, the enantiopure storage forms of chiral N-acyliminium ions (4RS, 5S)-5- chloromethyl-4-methoxy-1, 3-oxazolidin-2-one (2) and (4RS, 5R)-4-methoxy-5-methyl-1, 3 ...
[Madhusudhan; Reddy, M. Srinivasa; Reddy, Y. Narayana; Vijayalakshmi; Suribabu; Balraju Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2010 , vol. 49, # 7 p. 978 - 984]