cyclophane (5) by the condensation of 2, 6-bis (mercaptomethy1) toluene with 3. In this case 5 was formed with the ratio of syn to anti isomcrs being 3: 2. Similar results have been reported by Vogtle and n'e~ mann.~ Even in this instance the repulsion of a single fluoro group apparently outweighs the greater strain energy associated with the syn conformation. The important consequencc of the formation of only the syn conformer of 4 was that we'i\' ...
