6-Alkyl-, 6-aryl-or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents

P Perlíková, P Konečný, P Nauš, J Snášel, I Votruba…

Index: MedChemComm, , vol. 4, # 11 p. 1497 - 1500

Full Text: HTML

Citation Number: 10

Abstract

... equiv)/DMF, 105 °C; (iv) R–B(OH) 2 (1.5 equiv), K 2 CO 3 (2 equiv), Pd(PPh 3 ) 4 (0.05 equiv ... We thank Mrs Dagmar Grundová for excellent technical assistance. ... Lett., 2001, 11, 1675–1678 CrossRef CAS ; (b) AK Pathak, V. Pathak, LE Seitz, WJ Suling and RC Reynolds, J. Med. ...