The reaction of sodium nitromalonaldehyde (I) with ethyl p-aminocrotonate (11) was studied as part of a program of synthesis of new heterocyclic compounds of possible pharmacological interest. The only product isolated from the reaction mixture was ethyl 2- methyl-5-nitronicotinate (111). This is the lirst reported use of sodium nitromalonaldedehvde for the synthesis of a nitropyridine. 2 The
