Asian Journal of Chemistry

Synthesis of N-Methyl L-Phenylalanine for Total Synthesis of Pepticinnamin E

D Sun, L Zhang, J Wang

Index: Sun, Dequn; Zhang, Lingzi; Wang, Jin Asian Journal of Chemistry, 2012 , vol. 24, # 1 p. 319 - 322

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Abstract

Abstract The target compounds 3, 10 and 11 were synthesized through different N- methylation strategies. The concise and efficient preparation of them in large scale was developed and 3, 10 and 11 were obtained in suitable form used for both nitrogen-end and oxygen-end extension in next coupling reaction in peptides synthesis, specifically in total synthesis of natural pepticinnamin E.