Synthesis and Quantum Chemical Studies of New 4??aminoquinazoline Derivatives as Aurora A/B Kinase Inhibitors

M Zheng, Y Zheng, Y Xue, Y Liu, L An…

Index: Chemical Biology and Drug Design, , vol. 81, # 3 p. 399 - 407

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Citation Number: 2

Abstract

... Chemical Biology & Drug Design, 81: 399–407. ... Chemistry. ... Quantum chemical calculation of electronic parameters including HOMO and LUMO indicates an association of molecular orbitals at low energy with antiproliferation activities of these compounds. ...