Structure–activity relationships of privileged structures lead to the discovery of novel biased ligands at the dopamine D2 receptor

M Szabo, C Klein Herenbrink…

Index: Abdel-Fattah, Mohamed A. O.; Lehmann, Jochen; Abadi, Ashraf H. Chemistry and Biodiversity, 2013 , vol. 10, # 12 p. 2247 - 2266

Full Text: HTML

Citation Number: 22

Abstract

... 4939. DOI: 10.1021/jm500457x. Publication Date (Web): May 14, 2014. Copyright © 2014 American Chemical Society. ... Chemistry Derivatives of the previously described privileged structures (5–7) were synthesized utilizing a single ... (a) BOP reagent, DIPEA, DMF, rt, 1–12 h, 29–70 ...