The imidazole ring system is an important nucleus for drug discovery and as such represents the core structure of a number of biologically significant molecules. Iminoimidazolines (2??arylimino??2??imidazolines) are effective pharmacophores in medicinal chemistry.11. Gust , R. , Busch , S. , Keilitz , R. , Schmidt , K. and von Rauch , M. 2003. Investigations on the influence of halide substituents on the estrogen receptor interaction of 2,4,5??tris(4??hydroxy phenyl) ...
[Sharma, S. D.; Arora, S. K.; Mehra, Usha Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 895 - 901]