Palladium-catalyzed reaction of 2-iodoferrocenyl alcohols with internal alkynes: Synthesis of functionally 1, 2-disubstituted ferrocenes and ferroceno-pyrans

B Yucel, B Sanli, H Soylemez, H Akbulut

Index: Yucel, Baris; Sanli, Bahar; Soylemez, Huseyin; Akbulut, Huseyin Journal of Organometallic Chemistry, 2012 , vol. 704, p. 49 - 64

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Citation Number: 5

Abstract

The reaction of racemic (2-iodoferrocenyl) methanol with internal alkynes in the presence of (dppf) PdCl2 and i-Pr2NH produces alkenyl-substituted ferrocene carboxaldehydes in moderate yields. All reactions are carried out at 100 or 120° C for different reaction times (between 6 and 26 h) in a screw-cap Pyrex bottle. The scope and limitations of this reaction are studied by employing variously substituted 11 internal alkynes. The reactions are ...