Tetrahedron

Asymmetric induction—V: Effect of R on asymmetric induction in additions to abcC-COR compounds

C Zioudrou, I Moustakali-Mavridis, P Chrysochou…

Index: Zioudrou,C. et al. Tetrahedron, 1978 , vol. 34, p. 3181 - 3186

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Citation Number: 13

Abstract

The diastereomeric product ratios from reactions involving the addition of various reagents to the carbonyl of φCH3HC-COR compounds varies over a wide range. This variation is interpreted as due partly to changes in the structure of the diastereomeric transition states with changes in the size of R. For example, when R is smaller than the φCH3HC group the diastereomeric product ratios are close to those predicted on the assumption that 1 and 2 ...