From azido acids to macrolactams and macrolactones

…, V Bou, J Garcia, F Urpi, J Vilarrasa

Index: Bartra, Marti; Bou, Valenti; Garcia, Jordi; Urpi, Felix; Vilarrasa, Jaume Journal of the Chemical Society, Chemical Communications, 1988 , # 4 p. 270 - 272

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Citation Number: 1

Abstract

A new method is reported for the conversion of azido acids into lactams, via thioester formation and in situ azide reduction and cyclisation under high-dilution conditions; since the quantitative conversion of macrolactams to macrolactones has been shown to be feasible, this results in an indirect, alternative macrolactonisation procedure.