A Novel Synthesis of Highly Substituted Perhydropyrrolizines, Perhydroindolizines, and Pyrrolidines: Inhibition of the Peptidyl??Prolyl cis/trans Isomerase (PPIase) Pin1

R Siegrist, M Zürcher, C Baumgartner…

Index: Helvetica Chimica Acta, , vol. 90, # 2 p. 217 - 259

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Citation Number: 15

Abstract

... (+)-33c H MeO naphthalen-2-yl PhCH2 P(O)(OH)2 9 (À)-38c H MeO naphthalen-2-yl PhCH2 H inactive a) Uncertainties in Ki : Æ10 – 20%. b) Piperonyl=(1,3-benzodioxol- 5-yl)methyl. Helvetica Chimica Acta – Vol. 90 (2007) 230 Page 15. ...