Polyhydroxylated piperidines, commonly known as azasugars (iminosugars), are a class of compounds in which the ring oxygen of the sugar ring is replaced by nitrogen. At physiological pH, this nitrogen can be protonated and mimics a glycopyranosyl cation. In recent years, these polyhydroxylated compounds have attracted a great deal of attention, mainly due to their special structural features and promising biological activities. 1 Polyhydroxylated piperidines have the ability to ...