Synlett

A ligand-free copper-catalyzed decarboxylative trifluoromethylation of aryliodides with sodium trifluoroacetate using Ag2O as a promoter

…, T Chen, H Wang, R Zhang, K Jin, X Wang, C Duan

Index: Li, Yaming; Chen, Tao; Wang, Huifeng; Zhang, Rong; Jin, Kun; Wang, Xiuna; Duan, Chunying Synlett, 2011 , # 12 p. 1713 - 1716

Full Text: HTML

Citation Number: 31

Abstract

Abstract A practical and ligand-free Cu-catalyzed decarboxylative trifluoromethylation of aryl iodides with sodium trifluoroacetate using Ag 2 O as a promoter was reported. A variety of trifluoromethyl-substituted aromatics are synthesized in moderate to excellent yields and with wide functional-group tolerance under relatively mild reaction conditions.