e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
1,. omega.-Perfluoroalkylation of aromatics via bis-decarboxylation of perfluorodicarboxylic acids with xenon difluoride
VK Brel, VI Uvarov, NS Zefirov, PJ Stang…
Index: Brel, Valery K.; Uvarov, Viktor I.; Zefirov, Nikolai S.; Stang, Peter J.; Caple, Ron Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6922 - 6923
It has been shown that fluoro-substituted aliphatic acids reacts with xenon difluoride, XeF,, to give unstable derivatives of the type (RC00) ZXe or RCOOXeF'which, in turn, undergo a spontaneous decarboxylative decomposition leading to the formation of fluoroalkyl radicals. 2 This process has been suggested as a new preparative procedure to introduce a fluorinated alkyl framework into a variety of organic molecule^.^ The goal of the present ...
