e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii

S Lourido, C Zhang, MS Lopez, K Tang…

Index: Journal of Medicinal Chemistry, , vol. 56, # 7 p. 3068 - 3077

Full Text: HTML

Citation Number: 28

Abstract

... Journal of Medicinal Chemistry. ... Louis Missouri 63110, United States. § Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, UC San Francisco, 600 16th Street, San Francisco, California 94143, United States. J. Med. Chem. ...

naphthoic acid Structure

~%

1-Naphthyl(methoxy) Propanedinitrile Structure

1-Naphthyl(meth...

2-(1-Naphthalenylcarbonyl)-propanedinitrile Structure

2-(1-Naphthalen...

Dimethyl sulfate Structure

Dimethyl sulfate

~%

1-Naphthyl(methoxy) Propanedinitrile Structure

1-Naphthyl(meth...

naphthoic acid Structure

~%

2-(1-Naphthalenylcarbonyl)-propanedinitrile Structure

2-(1-Naphthalen...

tert-butylhydrazine Structure

tert-butylhydrazine

[1-Methoxy-2-(1-naphthyl)ethylidene]malononitrile Structure

[1-Methoxy-2-(1...

~%

4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYLMETHYL)-4-CYANOPYRAZOLE Structure

4-AMINO-1-TERT-...

m-Tolylacetic acid Structure

m-Tolylacetic acid

~%

5-Amino-1-tert-butyl-3-(3-methylbenzyl)-4-cyanopyrazole Structure

5-Amino-1-tert-...

M-TOLYLACETYLCHLORIDE Structure

M-TOLYLACETYLCH...

~%

5-Amino-1-tert-butyl-3-(3-methylbenzyl)-4-cyanopyrazole Structure

5-Amino-1-tert-...

tert-butylhydrazine Structure

tert-butylhydrazine

2-(1-methoxy-2-(m-tolyl)ethylidene)malononitrile Structure

2-(1-methoxy-2-...

~%

5-Amino-1-tert-butyl-3-(3-methylbenzyl)-4-cyanopyrazole Structure

5-Amino-1-tert-...

naphthoic acid Structure

~%

5-Amino-3-(1-naphthyl)-4-cyano-1-tert-butylpyrazole Structure

5-Amino-3-(1-na...

2-(1-Naphthalenylcarbonyl)-propanedinitrile Structure

2-(1-Naphthalen...

~%

5-Amino-3-(1-naphthyl)-4-cyano-1-tert-butylpyrazole Structure

5-Amino-3-(1-na...

tert-butylhydrazine Structure

tert-butylhydrazine

1-Naphthyl(methoxy) Propanedinitrile Structure

1-Naphthyl(meth...

~%

5-Amino-3-(1-naphthyl)-4-cyano-1-tert-butylpyrazole Structure

5-Amino-3-(1-na...

Generation of monospecific nanomolar tyrosine kinase inhibit...

[Journal of the American Chemical Society, , vol. 121, # 4 p. 627 - 631]