Dramatic reversal of diastereoselectivity in an N-acyliminium ion cyclization leading to hexahydropyrrolo [2, 1-a] isoquinolines. A case of competing steric interactions

BE Maryanoff, DF McComsey…

Index: Journal of Organic Chemistry, , vol. 51, # 8 p. 1341 - 1346

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Citation Number: 27

Abstract

... (b) Jackman, LM; Sternhell, S. "Applications of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry", 2nd ed.; Per- gamon Press: Oxford, 1969; pp 334-338. (10) Jelinski, LW Chem. Eng. ... Aue, WP; Bartholdi, E; Ernst, RR J. Chem. Phys. 1976, 64, 2229. ...