Synthesis of 2-Oxazolone-4-carboxylates from 3-Nosyloxy-and 3-Bromo-2-ketoesters

JF Okonya, RV Hoffman…

Index: Cornwall, Philip; Dell, Colin P.; Knight, David W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 10 p. 2417 - 2428

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Citation Number: 33

Abstract

... The Journal of Organic Chemistry. ... This reactivity pattern led us to explore acid-catalyzed additions of weak, nonbasic nucleophiles to 2. We were pleased to find that condensation of 3-nosyloxy-2-ketoester 2a with methyl carbamate and p-TSA in refluxing toluene ...