Tetrahedron letters

A new approach to the 1, 10-phenanthroline core

G Chelucci, D Addis, S Baldino

Index: Chelucci, Giorgio; Addis, Daniele; Baldino, Salvatore Tetrahedron Letters, 2007 , vol. 48, # 19 p. 3359 - 3362

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Citation Number: 16

Abstract

A protocol for the synthesis of substituted 1, 10-phenanthrolines is reported. The phenanthroline scaffold has been obtained constructing the central cycle starting from two pyridine rings. The method is hinged upon the intramolecular coupling of cis-1, 2-di (2- bromo-3-pyridyl) ethenes that are in turn obtained from the Wittig reaction of 2- bromonicotinaldehydes with phosphonium salts prepared from 2-bromo-3-(bromomethyl) ...