e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Organic letters

A Catalytic Asymmetric Route to Carbapenems

MJ Bodner, RM Phelan, CA Townsend

Index: Organic Letters, , vol. 11, # 16 p. 3606 - 3609

Full Text: HTML

Citation Number: 18

Abstract

... Volume: Page: ... Organic Letters. ... 10e) We reasoned that if this system could be applied to carbapenem synthesis, catalyst choice would determine the C-5 and C-6 stereocenters and enantiopure ketenes could be employed to establish that at C-8.(11, 12) Various ...

(3S,4R)-benzyl N-(p-toluenesulfonyl)-3-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-azetidin-2-one-4-carboxylate Structure

(3S,4R)-benzyl ...

~%

p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate Structure

p-Nitrobenzyl (...

(3R,4R)-4-acetoxy-3-[(1R)-1-(tert-butyldimethylsilyloxy)ethyl]-2-oxoazetidine Structure

(3R,4R)-4-aceto...

~%

p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate Structure

p-Nitrobenzyl (...

p-nitrobenzyl 2-diazo-3-(tert-butyldimethylsililoxy)-3-butenoate Structure

p-nitrobenzyl 2...

~%

p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate Structure

p-Nitrobenzyl (...

(3S,4R)-3-[(R)-1'-(dimethyl-t-butylsilyloxy)ethyl]-4-oxoazetidin-2-carboxylic acid Structure

(3S,4R)-3-[(R)-...

~%

p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate Structure

p-Nitrobenzyl (...

N/A Structure

~%

p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate Structure

p-Nitrobenzyl (...

(3S,4R)-benzyl 3-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-azetidin-2-one-4-carboxylate Structure

(3S,4R)-benzyl ...

~%

p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate Structure

p-Nitrobenzyl (...

(3S,4R)-benzyl N-(p-toluenesulfonyl)-3-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-azetidin-2-one-4-carboxylate Structure

(3S,4R)-benzyl ...

~%

UNII:V9J4CAR06A Structure

UNII:V9J4CAR06A

(3S,4R)-benzyl 3-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-azetidin-2-one-4-carboxylate Structure

(3S,4R)-benzyl ...

~%

UNII:V9J4CAR06A Structure

UNII:V9J4CAR06A

(3R,4R)-4-acetoxy-3-[(1R)-1-(tert-butyldimethylsilyloxy)ethyl]-2-oxoazetidine Structure

(3R,4R)-4-aceto...

~%

UNII:V9J4CAR06A Structure

UNII:V9J4CAR06A

p-nitrobenzyl 2-diazo-3-(tert-butyldimethylsililoxy)-3-butenoate Structure

p-nitrobenzyl 2...

~%

UNII:V9J4CAR06A Structure

UNII:V9J4CAR06A

(3S,4R)-3-[(R)-1'-(dimethyl-t-butylsilyloxy)ethyl]-4-oxoazetidin-2-carboxylic acid Structure

(3S,4R)-3-[(R)-...

~%

UNII:V9J4CAR06A Structure

UNII:V9J4CAR06A

N/A Structure

~%

UNII:V9J4CAR06A Structure

UNII:V9J4CAR06A

A stereocontrolled synthesis of (+)-thienamycin

[Journal of the American Chemical Society, , vol. 102, # 19 p. 6161 - 6163]

A stereocontrolled synthesis of (+)-thienamycin

[Journal of the American Chemical Society, , vol. 102, # 19 p. 6161 - 6163]

A stereocontrolled synthesis of (+)-thienamycin

[Journal of the American Chemical Society, , vol. 102, # 19 p. 6161 - 6163]

A stereocontrolled synthesis of (+)-thienamycin

[Journal of the American Chemical Society, , vol. 102, # 19 p. 6161 - 6163]

A stereocontrolled synthesis of (+)-thienamycin

[Journal of the American Chemical Society, , vol. 102, # 19 p. 6161 - 6163]