Synthesis of 3??Amino??2??(3??indolyl) propanol and Propanoate Derivatives and Preliminary Cardiovascular Evaluation in Rats

…, E HONG, P JOSEPH??NATHAN

Index: Perez-Alvarez, Victor; Morales-Rios, Martha S.; Hong, Enrique; Joseph-Nathan, Pedro Journal of Pharmacy and Pharmacology, 1997 , vol. 49, # 3 p. 246 - 252

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Citation Number: 6

Abstract

... VICTOR PEREZ-ALVAREZ, MARTHA s. MORALES-R~OS*, ENRIQUE HONG AND PEDRO JOSEPH-NATHAN* ... Preparation of 3-amino-2-(S-benzylo~-lH-indol-3-yl)propa- no1 oxalate (2c) Aqueous KzCO3 (6%; 40 mL) was added to a suspension of lc (500 mg; 1.38 mmol) in CHzCl2 (85 mL) and the mixture was stirred vigorously at room temp for 30 min. ... One or two Page 5. 250 VICTOR PEREZ-ALVAREZ ET AL Table 1. hypertensive rats. ...