Chemical Communications

Efficient cyclization of tertiary amines and alkenes promoted by KO t-Bu–DMF

Y Chen, X Zhang, H Yuan, W Wei, M Yan

Index: Chen, Yan-Yan; Zhang, Xue-Jing; Yuan, Hui-Min; Wei, Wen-Tao; Yan, Ming Chemical Communications, 2013 , vol. 49, # 93 p. 10974 - 10976

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Citation Number: 14

Abstract

Nitrogen heterocycles are most privileged structures in natural products and synthetic drugs. Their synthetic methods have been receiving great attention. 1 In recent years, there have been increasing interest in the direct functionalization of α C–H bonds of amines. 2 The strategy provides superior advantages over the traditional methods in terms of synthetic efficiency, atom economy and green chemistry. Typical activation modes of α C–H bonds ...