Functionalized calixspherands: synthesis and peptide coupling

…, M Haas, HJ den Hertog Jr, W Verboom…

Index: Bakker, Wouter I. Iwema; Haas, Marijke; Hertog, Herman J. den; Verboom, Willem; Zeeuw, Dick de; et al. Journal of Organic Chemistry, 1994 , vol. 59, # 5 p. 972 - 976

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Citation Number: 14

Abstract

Calixspherands, like 1, form kinetically stable complexes with alkali metal cations. For practical in uiuo applications coupling of these complexes with carrier molecules is mandatory. Therefore, a general method for the synthesis of functionalized calixspherand 17 was developed starting from functionalized m-terphenyl 10 and p-tert-butylcalix [4] arene (14). The functionalized m-terphenyl was synthesized by a Suzuki-cross-coupling reaction ...